Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372254 | 0.82 | NPC1 (0.34) | NPC1TSHRKMT2AMEN1RXFP1 | |
| SCHEMBL19601483 | 0.79 | TSHR (0.34) | NPC1TSHRKMT2AMEN1RXFP1 | |
| SCHEMBL14505866 | 0.78 | MEN1 (0.36) | KMT2AMEN1RXFP1GAA | |
| SCHEMBL14505498 | 0.76 | POLB (0.40) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL14505567 | 0.76 | ALDH1A1 (0.34) | NPC1TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL19608723 | 0.76 | PTGS1 (0.37) | TSHRKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL14505888 | 0.75 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL13208398 | 0.75 | RXFP1 (0.34) | NPC1KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL14505549 | 0.74 | MEN1 (0.36) | NPC1KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL9972653 | 0.68 | GAA (0.35) | NPC1TSHRALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-14 | — | — | US | disclosed |
| US-20170325459-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-16 | — | — | US | disclosed |
| WO-2016087371-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
| US-7855166-B2 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2010-12-21 | — | — | US | disclosed |
| US-7855166-B2 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2010-12-21 | — | — | US | disclosed |
| US-RE39607-E1 | Herbicidal sulphonylamino(thio) carbonyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-RE39607-E1 | Herbicidal sulphonylamino(thio) carbonyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170325459-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | NPC1 2214/4885TSHR 4369/4885KMT2A 1850/4885 |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | NPC1 1939/4885TSHR 4161/4885KMT2A 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.