Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | RGS4 | P49798 | 1/20 | 0.31 |
| ▸ | RGS8 | P57771 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608723 | 0.82 | PTGS1 (0.37) | MAPK1TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL13006850 | 0.82 | NPC1 (0.37) | NPC1MAPK1TSHRALDH1A1HPGD | |
| SCHEMBL19601483 | 0.74 | TSHR (0.34) | NPC1MAPK1TSHRALDH1A1HPGD | |
| SCHEMBL6760748 | 0.71 | BRD9 (0.41) | NPC1ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL14372251 | 0.69 | RGS4 (0.33) | RGS4RGS8 | |
| SCHEMBL12012284 | 0.68 | TSHR (0.34) | MAPK1TSHRALDH1A1HSD17B10GAA | |
| SCHEMBL19705467 | 0.67 | RGS4 (0.32) | MAPK1MEN1KMT2ARXFP1HTT | |
| SCHEMBL15782232 | 0.67 | BRD9 (0.33) | KMT2AGAARGS4RGS8 | |
| SCHEMBL14372246 | 0.67 | RGS4 (0.31) | ALDH1A1KMT2AGAARGS4RGS8 | |
| SCHEMBL6760743 | 0.67 | BRD9 (0.39) | MAPK1MEN1KMT2ARGS4RGS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |