Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848939 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAHTTHPGDMEN1 | |
| SCHEMBL6670720 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25056999 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTHPGDHSD17B10 | |
| SCHEMBL17234481 | 0.75 | ALDH1A1 (0.60) | ALDH1A1LMNAHTTHPGDMEN1 | |
| SCHEMBL6490227 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HPGDNPC1MAPK8 | |
| SCHEMBL1268978 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HTTHPGDNPC1RAB9A | |
| SCHEMBL18794901 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTHPGDMEN1 | |
| SCHEMBL5509361 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTHPGDMEN1 | |
| SCHEMBL6498162 | 0.73 | ALDH1A1 (0.43) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL23107659 | 0.72 | ALDH1A1 (0.62) | ALDH1A1LMNAHTTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723255-B1 | METHOD FOR ENRICHMENT INVOLVING ELIMINATION BY MISMATCH HYBRIDISATION | NUEVOLUTION AS (DK) | 2010-12-29 | — | — | EP | disclosed |