SCHEMBL1300780

SCHEMBL1300780

COC(=O)C(N)CC(C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.48
SLC7A5 Q01650 1/20 0.45
FOLH1 Q04609 2/20 0.44
NAALAD2 Q9Y3Q0 2/20 0.44
SLC1A1 P43005 3/20 0.41
SLC1A3 P43003 3/20 0.41
SLC1A2 P43004 3/20 0.41
GABRR1 P24046 2/20 0.40
MME P08473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7557051 0.87 SMN1; SMN2 (0.38) ENPEPSLC7A5SLC1A1SLC1A3SLC1A2
SCHEMBL6933793 0.87 SMN1; SMN2 (0.38) ENPEPSLC7A5SLC1A1SLC1A3SLC1A2
SCHEMBL3260973 0.83 SLC7A5 (0.56) ENPEPSLC7A5SLC1A1SLC1A3SLC1A2
SCHEMBL28746682 0.83 SLC7A5 (0.56) ENPEPSLC7A5SLC1A1SLC1A3SLC1A2
SCHEMBL8894673 0.82 SMN1; SMN2 (0.42) SLC7A5SLC1A1SLC1A3SLC1A2
Alanine SCHEMBL7256054 0.82 SLC7A5 (0.59) SLC7A5FOLH1SLC1A1SLC1A3SLC1A2
SCHEMBL1301349 0.82 ENPEP (0.47) ENPEPSLC7A5FOLH1NAALAD2SLC1A1
Leucine SCHEMBL10382490 0.82 SLC7A5 (0.72) SLC7A5FOLH1SLC1A1SLC1A3SLC1A2
SCHEMBL76796 0.80 SLC7A5 (0.56) SLC7A5FOLH1SLC1A3SLC1A2MME
SCHEMBL196338 0.80 SLC7A5 (0.56) SLC7A5FOLH1SLC1A3SLC1A2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023636-B2 Microorganisms and methods for the biosynthesis of propylene GENOMATICA, INC. (US) 2015-05-05 US disclosed
US-8617862-B2 Microorganisms for producing propylene and methods related thereto GENOMATICA, INC. (US) 2013-12-31 US disclosed
EP-2563926-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE Genomatica, Inc. (US) 2013-03-06 EP disclosed
US-20120329119-A1 MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO GENOMATICA, INC. 2012-12-27 US disclosed
WO-2011137198-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE GENOMATICA, INC. (US) 2011-11-03 WO disclosed
US-20110269204-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE AGAIN BIO APS (DK) 2011-11-03 US disclosed