SCHEMBL1301349

SCHEMBL1301349

CCOC(=O)C(N)CC(C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.47
SLC7A5 Q01650 1/20 0.43
SLC1A3 P43003 5/20 0.39
SLC1A2 P43004 5/20 0.39
SLC1A1 P43005 4/20 0.39
GABRR1 P24046 2/20 0.39
FOLH1 Q04609 2/20 0.38
NAALAD2 Q9Y3Q0 2/20 0.38
ALOX15 P16050 1/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
NOD1 Q9Y239 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7557066 0.88 CYP2C19 (0.45) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
SCHEMBL7554622 0.88 CYP2C19 (0.45) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
SCHEMBL8894678 0.83 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
SCHEMBL14016339 0.83 ALOX15 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
SCHEMBL1300780 0.82 ENPEP (0.48) ENPEPSLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL196637 0.81 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ALOX15
SCHEMBL133092 0.81 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ALOX15
SCHEMBL839402 0.81 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ALOX15
SCHEMBL11072837 0.81 CYP3A4 (0.50) ENPEPGABRR1FOLH1NAALAD2ALOX15
SCHEMBL11072835 0.81 CYP3A4 (0.50) ENPEPGABRR1FOLH1NAALAD2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023636-B2 Microorganisms and methods for the biosynthesis of propylene GENOMATICA, INC. (US) 2015-05-05 US disclosed
US-8617862-B2 Microorganisms for producing propylene and methods related thereto GENOMATICA, INC. (US) 2013-12-31 US disclosed
EP-2563926-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE Genomatica, Inc. (US) 2013-03-06 EP disclosed
US-20120329119-A1 MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO GENOMATICA, INC. 2012-12-27 US disclosed
WO-2011137198-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE GENOMATICA, INC. (US) 2011-11-03 WO disclosed
US-20110269204-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE AGAIN BIO APS (DK) 2011-11-03 US disclosed