SCHEMBL13008945

SCHEMBL13008945

CC1(C)c2cc(-c3ccccc3)ccc2-c2ccc(-c3c4ccc(N5c6ccccc6C(C)(C)c6ccccc65)cc4c(-c4ccc5ccccc5c4)c4ccc(N5c6ccccc6C(C)(C)c6ccccc65)cc34)cc21

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
PDK2 Q15119 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
AKT1 P31749 1/20 0.31
PDE6D O43924 1/20 0.31
ESR1 P03372 2/20 0.30
ESR2 Q92731 2/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13009270 0.96 PDK2 (0.34) PDK2PDE6DESR1ESR2
SCHEMBL13427504 0.95 LPL (0.32) LPLLIPGPDK2ALDH1A1KDM4E
SCHEMBL13009451 0.95 LPL (0.35) LPLLIPGALDH1A1KDM4EMEN1
SCHEMBL13009458 0.94 PDK2 (0.33) PDK2ALDH1A1KDM4EMEN1MAPT
SCHEMBL13427431 0.94 PDK2 (0.33) PDK2ALDH1A1KDM4EMEN1MAPT
SCHEMBL13008853 0.94 ALDH1A1 (0.32) ALDH1A1KDM4EMEN1MAPTHTT
SCHEMBL13427425 0.94 ALDH1A1 (0.32) ALDH1A1KDM4EMEN1MAPTHTT
SCHEMBL13008772 0.93 AKT1 (0.37) LPLLIPGALDH1A1KDM4EMEN1
SCHEMBL13427419 0.92 ESR1 (0.35) LPLLIPGALDH1A1KDM4EMEN1
SCHEMBL13427427 0.92 KMT2A (0.34) LPLLIPGALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256176-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-12-01 EP disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A LPL 4521/4885LIPG 4672/4885PDK2 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.