Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 19/20 | 0.78 |
| ▸ | CTSG | P08311 | 2/20 | 0.77 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.77 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.77 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654773 | 0.88 | CMA1 (1.00) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL404228 | 0.87 | CMA1 (1.00) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL998105 | 0.87 | CMA1 (0.78) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL31476750 | 0.87 | CMA1 (1.00) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL999231 | 0.87 | CMA1 (0.78) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL23752344 | 0.87 | CMA1 (1.00) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL409547 | 0.87 | CMA1 (0.78) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL409986 | 0.86 | CMA1 (0.77) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL998748 | 0.81 | CMA1 (0.78) | CMA1CTSGPRSS1PRSS2PRSS3 | |
| SCHEMBL13490189 | 0.79 | CMA1 (0.65) | CMA1CTSGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716160-B1 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-29 | — | — | EP | disclosed |