Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 9/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL1319588 | 0.92 | PRKCI (0.44) | PRKCICDK8FYNS1PR1S1PR3 | |
| SCHEMBL3650445 | 0.84 | PRKCI (0.51) | PRKCICDK8FYNS1PR1S1PR3 | |
| SCHEMBL31500156 | 0.84 | CYP4F2 (0.46) | S1PR1 | |
| SCHEMBL1579740 | 0.83 | ADRB2 (0.46) | CDK8 | |
| SCHEMBL13181038 | 0.83 | NPC1 (0.40) | ADORA2AADORA1 | |
| SCHEMBL31500185 | 0.83 | PRKCI (0.50) | PRKCICDK8FYNS1PR1S1PR3 | |
| SCHEMBL1581550 | 0.83 | PRKCI (0.50) | PRKCICDK8FYNS1PR1S1PR3 | |
| SCHEMBL3650131 | 0.83 | PRKCI (0.50) | PRKCICDK8FYNS1PR1S1PR3 | |
| SCHEMBL13285567 | 0.83 | PRKCI (0.50) | PRKCICDK8FYNS1PR1S1PR3 | |
| SCHEMBL29550622 | 0.83 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010850-A | Synthesis method of 3- (5-bromopyrimidinyl) benzyl alcohol | 广东莱佛士制药技术有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122010850-A | Synthesis method of 3- (5-bromopyrimidinyl) benzyl alcohol | 广东莱佛士制药技术有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122010850-A | Synthesis method of 3- (5-bromopyrimidinyl) benzyl alcohol | 广东莱佛士制药技术有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122010850-A | Synthesis method of 3- (5-bromopyrimidinyl) benzyl alcohol | 广东莱佛士制药技术有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-119968355-A | Cyclopentane compounds | 橘生药品工业株式会社 | 2025-05-09 | — | — | CN | disclosed |
| CN-118406014-A | Benzyl 3- (5-halogenopyrimidinyl) carboxylate, and preparation method and application thereof | 上海法默生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| WO-2024112122-A1 | DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |
| CN-114736191-B | Terpetinib intermediate and preparation method and application thereof | 上海工程技术大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-114736191-A | Tepritinib intermediate and preparation method and application thereof | 上海工程技术大学 | 2022-07-12 | — | — | CN | disclosed |
| EP-2310013-B1 | BICYCLIC TRIAZOLE DERIVATIVES FOR TREATING TUMORS | MERCK PATENT GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2164843-A1 | PYRIDAZINONE DERIVATES | Merck Patent GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2010017870-A1 | BICYCLIC TRIAZOLE DERIVATIVES FOR TREATING TUMORS | MERCK PATENT GMBH (DE) | 2010-02-18 | — | — | WO | disclosed |
| EP-2150551-A1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | Merck Patent GmbH (DE) | 2010-02-10 | — | — | EP | disclosed |
| WO-2009083076-A1 | 2-BENZYLPYRIDAZINONE DERIVATIVES AS MET KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083076-A1 | 2-BENZYLPYRIDAZINONE DERIVATIVES AS MET KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009030333-A1 | THIADIAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030333-A1 | THIADIAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2008148449-A1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | WO | disclosed |