Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909266 | 0.85 | POLB (0.40) | PIK3CDCYP2A6KIF11RAB9ADGAT1 | |
| SCHEMBL77078 | 0.85 | POLB (0.40) | PIK3CDCYP2A6KIF11RAB9ADGAT1 | |
| SCHEMBL11168653 | 0.82 | PIK3CD (0.52) | PIK3CDCYP2A6NOTUMKIF11NPC1 | |
| SCHEMBL12173603 | 0.81 | KIF11 (0.48) | KIF11NPC1RAB9ADGAT1ALDH1A1 | |
| SCHEMBL22002106 | 0.81 | ALOX5AP (0.39) | PIK3CDCYP2A6KIF11DGAT1ALDH1A1 | |
| SCHEMBL14327692 | 0.81 | ALOX5AP (0.39) | PIK3CDCYP2A6KIF11DGAT1ALDH1A1 | |
| SCHEMBL14848474 | 0.81 | SLC22A12 (0.40) | CYP2A6KIF11NPC1RAB9ADGAT1 | |
| SCHEMBL14062459 | 0.80 | KIF11 (0.52) | KIF11NPC1RAB9ADGAT1ALDH1A1 | |
| SCHEMBL14848446 | 0.79 | JAK2 (0.42) | CYP2A6KIF11NPC1 | |
| SCHEMBL10202995 | 0.79 | PIK3CD (0.48) | PIK3CDKIF11NPC1RAB9ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018220-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-28 | — | — | US | disclosed |
| US-8552007-B2 | Mesoionic pesticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20100323887-A1 | MESOIONIC PESTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323887-A1 | MESOIONIC PESTICIDES | DDT, CHRM1, CHRM3 | PIK3CD 2585/4885CYP2A6 1009/4885NOTUM 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.