SCHEMBL77078

SCHEMBL77078

CC(C)(C)c1ccc(Cl)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
LMNA P02545 2/20 0.40
RAB9A P51151 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PIK3CD O00329 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
TSHR P16473 1/20 0.39
KCNQ3 O43525 1/20 0.38
KCNQ2 O43526 1/20 0.38
KCNE1 P15382 1/20 0.38
KCNQ1 P51787 1/20 0.38
TYR P14679 1/20 0.37
KIF11 P52732 1/20 0.37
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909266 1.00 POLB (0.40) POLBLMNARAB9AATML3MBTL1
SCHEMBL13010754 0.85 PIK3CD (0.42) RAB9AALDH1A1PIK3CDNAPRTKIF11
SCHEMBL11168653 0.83 PIK3CD (0.52) POLBLMNARAB9AATML3MBTL1
SCHEMBL27311270 0.82 ALDH1A1 (0.37) POLBL3MBTL1ALDH1A1PIK3CDNAPRT
SCHEMBL29978443 0.82 MEN1 (0.41) POLBRAB9AALDH1A1PIK3CDNAPRT
SCHEMBL882392 0.82 PDE2A (0.42) ALDH1A1PIK3CDNAPRTKCNQ3KCNQ2
SCHEMBL29879160 0.82 KCNQ3 (0.42) POLBALDH1A1PIK3CDNAPRTKCNQ3
SCHEMBL248240 0.82 MEN1 (0.41) POLBRAB9AALDH1A1PIK3CDNAPRT
SCHEMBL9966941 0.82 KCNQ3 (0.42) POLBALDH1A1PIK3CDNAPRTKCNQ3
SCHEMBL25326819 0.79 KCNQ3 (0.41) POLBALDH1A1PIK3CDNAPRTKCNQ3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577208-B2 TEAD inhibitors and uses thereof EHE Foundation (US) 2026-03-17 US disclosed
US-20260076087-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-03-12 US disclosed
US-20260068416-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE BEIJING SUMMER SPROUT TECH CO LTD (CN) 2026-03-05 US disclosed
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-11-27 US disclosed
US-12391663-B2 Isoindolinone compounds MONTE ROSA THERAPEUTICS AG (CH) 2025-08-19 US disclosed
US-20250163063-A1 INHIBITORS OF CDK4/6 KINASE KHORA SPV 1, LLC 2025-05-22 US disclosed
US-20250154107-A1 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof BEIGENE SWITZERLAND GMBH (CH) 2025-05-15 US disclosed
CN-119954725-A TEAD inhibitors and uses thereof 医肯纳肿瘤学公司 2025-05-09 CN disclosed
US-20250089550-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2025-03-13 US disclosed
CN-119528988-A Organic electroluminescent material and device thereof 北京夏禾科技有限公司 2025-02-28 CN disclosed
US-20070213330-A1 Anticancer agents; antiproliferative agents METHYLGENE INC. (CA) 2007-09-13 US disclosed
US-7253204-B2 Antiproliferative agents METHYLGENE INC. (CA) 2007-08-07 US disclosed
US-20070161685-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2007-07-12 US disclosed
US-20070161685-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2007-07-12 US disclosed
US-20070135631-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2007-06-14 US disclosed
US-7214668-B2 Phosphonic acid based prodrugs of PMEA and its analogues METABASIS THERAPEUTICS, INC. (US) 2007-05-08 US disclosed
US-20070037794-A1 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides CHEMOCENTRYX, INC. 2007-02-15 US disclosed
US-20070037794-A1 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides CHEMOCENTRYX, INC. 2007-02-15 US disclosed
US-20070015771-A1 Lonidamine analogs THRESHOLD PHARMACEUTICALS, INC. (US) 2007-01-18 US disclosed
US-20070004701-A1 Topoisomerase inhibitors PROPHARMACON, INC. (US) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161685-A1 HETEROCYCLIC CETP INHIBITORS CETP, CES1, NPC1 POLB 380/4885LMNA 170/4885RAB9A 3451/4885
US-20260076087-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRB, OPRD1 POLB 1403/4885LMNA 58/4885RAB9A 489/4885
US-20070135631-A1 HETEROCYCLIC CETP INHIBITORS CETP, CES1, NPC1 POLB 380/4885LMNA 170/4885RAB9A 3451/4885
US-20070037794-A1 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides CCR2, CCR1, CCL2 POLB 4152/4885LMNA 4844/4885RAB9A 4692/4885
US-12391663-B2 Isoindolinone compounds CYP4F2, AOC2, AOC3 POLB 3996/4885LMNA 1164/4885RAB9A 3175/4885
US-20070213330-A1 Anticancer agents; antiproliferative agents HDAC1, HDAC11, HDAC5 POLB 450/4885LMNA 1962/4885RAB9A 3036/4885
US-20070004701-A1 Topoisomerase inhibitors TOP1, TOP2A, TOP2B POLB 15/4885LMNA 1934/4885RAB9A 3552/4885
US-20250089550-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, LEF1 POLB 3042/4885LMNA 1829/4885RAB9A 1337/4885
US-20070015771-A1 Lonidamine analogs LONP1, LPXN, QDPR POLB 600/4885LMNA 1353/4885RAB9A 2304/4885
US-20250163063-A1 INHIBITORS OF CDK4/6 KINASE CDK4, CDK6, CDK2 POLB 639/4885LMNA 1142/4885RAB9A 2766/4885
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS DGKG, DGKB, DGKK POLB 3027/4885LMNA 4186/4885RAB9A 1568/4885
US-20260068416-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE LEF1, MLX, L1CAM POLB 2947/4885LMNA 795/4885RAB9A 1501/4885
US-12577208-B2 TEAD inhibitors and uses thereof BRCA1, BRAF, MEN1 POLB 3826/4885LMNA 334/4885RAB9A 140/4885
US-20250154107-A1 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof STING1, IRF3, MAVS POLB 703/4885LMNA 1326/4885RAB9A 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.