Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706893 | 0.74 | LOXL2 (0.62) | NR3C1CYP4F2CYP4A11LOXL2SLC7A5 | |
| SCHEMBL165622 | 0.73 | LOXL2 (0.66) | NR3C1CYP4F2CYP4A11LOXL2SLC7A5 | |
| SCHEMBL6960295 | 0.73 | RAB9A (0.58) | CYP4F2CYP4A11LOXL2RAB9AALDH1A1 | |
| SCHEMBL12826775 | 0.72 | LOXL2 (0.50) | NR3C1CYP4F2CYP4A11LOXL2SLC7A5 | |
| SCHEMBL10106423 | 0.72 | LOXL2 (0.64) | NR3C1CYP4F2CYP4A11LOXL2SLC7A5 | |
| SCHEMBL1612858 | 0.72 | KMT2A (0.53) | NR3C1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL4490305 | 0.72 | LOXL2 (0.52) | NR3C1CYP4F2CYP4A11LOXL2SLC7A5 | |
| SCHEMBL21377435 | 0.71 | PTPN1 (0.64) | NR3C1CYP4F2CYP4A11LOXL2SLC7A5 | |
| SCHEMBL31276630 | 0.71 | CYP4F2 (0.75) | CYP4F2CYP4A11LOXL2SLC7A5RAB9A | |
| SCHEMBL40012 | 0.71 | CYP4F2 (0.75) | CYP4F2CYP4A11LOXL2SLC7A5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261206-A1 | INDOLINONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-12-15 | — | — | EP | disclosed |