Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 10/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13670872 | 0.90 | HDAC1 (0.47) | CETPHDAC1HDAC8HDAC6PIK3C3 | |
| SCHEMBL27778845 | 0.89 | HDAC1 (0.44) | CETPHDAC1HDAC8HDAC6PIK3C3 | |
| SCHEMBL13011721 | 0.86 | CETP (0.41) | CETPHDAC1HDAC8HDAC6PIK3C3 | |
| SCHEMBL3586830 | 0.85 | ALDH1A1 (0.47) | — | |
| SCHEMBL3586828 | 0.85 | ALDH1A1 (0.47) | — | |
| SCHEMBL2691178 | 0.83 | TNKS (0.49) | HDAC1HDAC8HDAC6HCRTR1HCRTR2 | |
| SCHEMBL2693640 | 0.83 | TNKS (0.49) | HDAC1HDAC8HDAC6HCRTR1HCRTR2 | |
| SCHEMBL2691174 | 0.83 | TNKS (0.49) | HDAC1HDAC8HDAC6HCRTR1HCRTR2 | |
| SCHEMBL3591787 | 0.81 | HDAC1 (0.42) | CETPHDAC1HDAC8HDAC6MCHR1 | |
| SCHEMBL3596493 | 0.81 | HDAC1 (0.42) | CETPHDAC1HDAC8HDAC6MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094684-B1 | 1,5-DIPHENYL-3-BENZYLAMINO-1,5-DIHYDROPYRROLIDIN 2-ONES AS CB1 RECEPTOR MODULATORS | LILLY CO ELI (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2008070306-A2 | 1,5-DIPHENYL-3-BENZYLAMIN0-1,5-DIHYDR0PYRR0LIDIN-2-0NE AS CB1 RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |