SCHEMBL1301295

SCHEMBL1301295

CCCC1CCCCCCCCCCCC(=O)O1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.54
NOS1 P29475 4/20 0.39
NOS2 P35228 4/20 0.39
NOS3 P29474 3/20 0.39
PPARG P37231 1/20 0.38
CA1 P00915 2/20 0.36
CA9 Q16790 1/20 0.36
KMT2A Q03164 1/20 0.35
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15658728 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL11099421 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL15658146 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL15658234 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL24668103 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL24667636 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL5998582 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL2818882 1.00 CYP1A2 (0.54) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL1930905 0.98 CYP1A2 (0.56) CYP1A2NOS1NOS2NOS3PPARG
SCHEMBL310717 0.92 CYP1A2 (0.58) CYP1A2NOS1NOS2NOS3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2376467-B1 FRAGRANCE COMPOSITION KAO CORP (JP) 2014-03-12 EP claimed
US-8338361-B2 Fragrance composition KAO CORPORATION (JP) 2012-12-25 US claimed
US-20110269664-A1 FRAGRANCE COMPOSITION KAO CORPORATION (JP) 2011-11-03 US claimed
EP-2376467-A1 FRAGRANCE COMPOSITION Kao Corporation (JP) 2011-10-19 EP claimed
WO-2010082684-A1 FRAGRANCE COMPOSITION KAO CORPORATION (JP) 2010-07-22 WO claimed
US-20230332071-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF PHYTO TECH CORP. 2023-10-19 US disclosed
US-20230332071-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF PHYTO TECH CORP. 2023-10-19 US disclosed
US-20230332071-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF PHYTO TECH CORP. 2023-10-19 US disclosed
US-20230323244-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF PHYTO TECH CORP (US) 2023-10-12 US disclosed
US-20230323244-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF PHYTO TECH CORP (US) 2023-10-12 US disclosed
US-20230323244-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF PHYTO TECH CORP (US) 2023-10-12 US disclosed
US-11639483-B2 Macrocyclic musk lactones and uses thereof PHYTO TECH CORP. (US) 2023-05-02 US disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
EP-2376467-B1 FRAGRANCE COMPOSITION KAO CORP (JP) 2014-03-12 EP disclosed
CN-103343049-A Fragrance composition KAO CORP 2013-10-09 CN disclosed
US-8338361-B2 Fragrance composition KAO CORPORATION (JP) 2012-12-25 US disclosed
CN-102264718-A Perfume composition 2011-11-30 CN disclosed
US-20110269664-A1 FRAGRANCE COMPOSITION KAO CORPORATION (JP) 2011-11-03 US disclosed
EP-2376467-A1 FRAGRANCE COMPOSITION Kao Corporation (JP) 2011-10-19 EP disclosed
WO-2010082684-A1 FRAGRANCE COMPOSITION KAO CORPORATION (JP) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639483-B2 Macrocyclic musk lactones and uses thereof MGLL, UGCG, DAGLA CYP1A2 477/4885NOS1 2621/4885NOS2 1921/4885
US-20230323244-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF MGLL, UGCG, DAGLA CYP1A2 477/4885NOS1 2621/4885NOS2 1921/4885
US-20110269664-A1 FRAGRANCE COMPOSITION MSI2, MUS81, EMC1 CYP1A2 399/4885NOS1 515/4885NOS2 1262/4885
US-20230332071-A1 MACROCYCLIC MUSK LACTONES AND USES THEREOF MGLL, UGCG, DAGLA CYP1A2 477/4885NOS1 2621/4885NOS2 1921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.