Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 16/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131990 | 0.81 | NR1H2 (0.68) | NR1H2NR1H3SMN1; SMN2MLYCD | |
| SCHEMBL14636831 | 0.80 | NR1H2 (0.53) | NR1H2NR1H3MLYCD | |
| SCHEMBL128398 | 0.79 | NR1H2 (0.56) | NR1H2NR1H3SMN1; SMN2MLYCD | |
| SCHEMBL1512233 | 0.78 | NR1H3 (0.52) | NR1H2NR1H3MLYCD | |
| SCHEMBL130133 | 0.78 | NR1H2 (0.62) | NR1H2NR1H3MLYCD | |
| SCHEMBL17114565 | 0.78 | NR1H2 (0.52) | NR1H2NR1H3MLYCD | |
| Water SCHEMBL1684070 | 0.78 | NR1H2 (0.65) | NR1H2NR1H3SMN1; SMN2MLYCD | |
| SCHEMBL10698067 | 0.78 | NR1H2 (0.56) | NR1H2NR1H3SMN1; SMN2MLYCD | |
| SCHEMBL18378219 | 0.77 | TAAR1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL26114490 | 0.77 | NR1H2 (0.50) | NR1H2NR1H3MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | NR1H2 857/4885NR1H3 1338/4885SMN1; SMN2 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.