SCHEMBL130133

SCHEMBL130133

CCc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 17/20 0.62
NR1H3 Q13133 17/20 0.62
MLYCD O95822 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18202059 0.94 NR1H2 (0.56) NR1H2NR1H3MLYCD
SCHEMBL13324726 0.83 NR1H2 (0.59) NR1H2NR1H3MLYCD
SCHEMBL26406906 0.81 HSD11B1 (0.51) NR1H2NR1H3
SCHEMBL131990 0.81 NR1H2 (0.68) NR1H2NR1H3MLYCD
SCHEMBL14636831 0.80 NR1H2 (0.53) NR1H2NR1H3MLYCD
SCHEMBL6339219 0.79 MEN1 (0.42) NR1H2NR1H3
SCHEMBL23545620 0.79 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL20362695 0.79 NR1H2 (0.53) NR1H2NR1H3MLYCD
SCHEMBL13974812 0.79 NR1H2 (0.54) NR1H2NR1H3MLYCD
SCHEMBL17114565 0.78 NR1H2 (0.52) NR1H2NR1H3MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785845-B2 Composition FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-10851188-B2 Polymer compound for conductive polymer and method for producing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-12-01 US disclosed
EP-2681623-B1 PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST FILM FUJIFILM CORP (JP) 2019-07-10 EP disclosed
US-9663656-B2 Conductive polymer material and substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-30 US disclosed
US-20170114182-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-04-27 US disclosed
US-20170114182-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-04-27 US disclosed
US-8637220-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and resist film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-01-28 US disclosed
US-8450319-B2 Pyrrolopyridazinone compound UBE INDUSTRIES, LTD. (JP) 2013-05-28 US disclosed
US-8394774-B2 Pesticidal compositions DOW AGROSCIENCES, LLC. (US) 2013-03-12 US disclosed
EP-1982986-B1 PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR UBE INDUSTRIES (JP) 2012-03-07 EP disclosed
US-20120003583-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed
US-20100204165-A1 Pesticidal Compositions DOW AGROSCIENCES LLC (US) 2010-08-12 US disclosed
US-20090036453-A1 Pyrrolopyridazinone Compound UBE INDUSTRIES, LTD. (JP) 2009-02-05 US disclosed
EP-1982986-A1 PYRROLOPYRIDAZINONE COMPOUND Ube Industries, Ltd. (JP) 2008-10-22 EP disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-6943271-B2 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same CENTRAL GLASS COMPANY, LIMITED (JP) 2005-09-13 US disclosed
US-20040002612-A1 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same CENTRAL GLASS COMPANY, LIMITED (JP) 2004-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204165-A1 Pesticidal Compositions ACHE, DDT, PTMS NR1H2 4347/4885NR1H3 4320/4885MLYCD 367/4885
US-20040002612-A1 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same PFAS, AFF1, AFF2 NR1H2 4260/4885NR1H3 4179/4885MLYCD 3314/4885
US-11785845-B2 Composition ADH1A, ADH1C, SLC19A2 NR1H2 794/4885NR1H3 515/4885MLYCD 3157/4885
US-20170114182-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO DCLRE1A, ODC1, MRTO4 NR1H2 3460/4885NR1H3 3398/4885MLYCD 543/4885
US-20090036453-A1 Pyrrolopyridazinone Compound CBR3, CBR1, CYC1 NR1H2 857/4885NR1H3 1338/4885MLYCD 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.