Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 2/20 | 0.42 |
| ▸ | ARG2 | P78540 | 2/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301385 | 0.84 | CYP1A2 (0.41) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL7234392 | 0.83 | GABRR1 (0.40) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL7226602 | 0.83 | GABRR1 (0.40) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL7226603 | 0.83 | GABRR1 (0.40) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL563056 | 0.83 | CYP1A2 (0.52) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL3383450 | 0.83 | CYP1A2 (0.52) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL13540752 | 0.77 | GABRR1 (0.41) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL58260 | 0.77 | — | — | |
| SCHEMBL7386541 | 0.76 | GABRR1 (0.44) | CYP1A2GABRR1FOLH1NAALAD2ENPEP | |
| Hydrochloric Acid SCHEMBL1133986 | 0.74 | MEN1 (0.62) | CYP1A2MEN1ALDH1A1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023636-B2 | Microorganisms and methods for the biosynthesis of propylene | GENOMATICA, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-8617862-B2 | Microorganisms for producing propylene and methods related thereto | GENOMATICA, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2563926-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | Genomatica, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20120329119-A1 | MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO | GENOMATICA, INC. | 2012-12-27 | — | — | US | disclosed |
| WO-2011137198-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | GENOMATICA, INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110269204-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | AGAIN BIO APS (DK) | 2011-11-03 | — | — | US | disclosed |