Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | ARG1 | P05089 | 2/20 | 0.39 |
| ▸ | ARG2 | P78540 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226603 | 1.00 | GABRR1 (0.40) | GABRR1ARG1ARG2CYP1A2ENPEP | |
| SCHEMBL7234392 | 1.00 | GABRR1 (0.40) | GABRR1ARG1ARG2CYP1A2ENPEP | |
| SCHEMBL1301353 | 0.83 | CYP1A2 (0.48) | GABRR1ARG1ARG2CYP1A2ENPEP | |
| SCHEMBL3100826 | 0.83 | GRM2 (0.42) | ARG1ARG2CYP1A2MEN1ALDH1A1 | |
| SCHEMBL3100821 | 0.83 | GRM2 (0.42) | ARG1ARG2CYP1A2MEN1ALDH1A1 | |
| SCHEMBL1301385 | 0.80 | CYP1A2 (0.41) | GABRR1ARG1ARG2CYP1A2ENPEP | |
| SCHEMBL7386541 | 0.76 | GABRR1 (0.44) | GABRR1CYP1A2ENPEPGRM2GRM3 | |
| SCHEMBL1300782 | 0.74 | GABRR1 (0.43) | GABRR1ARG1ARG2CYP1A2ENPEP | |
| SCHEMBL10443300 | 0.74 | GABRR1 (0.43) | GABRR1ARG1ARG2CYP1A2ENPEP | |
| SCHEMBL10498366 | 0.74 | GABRR1 (0.43) | GABRR1ARG1ARG2CYP1A2ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599940-B2 | Neurotransmitters | GEORGETOWN UNIVERSITY | 2003-07-29 | — | — | US | disclosed |
| US-20020147362-A1 | Synthesis of 2-Hydroxymethylglutamic acid and congeners thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-10-10 | — | — | US | disclosed |
| WO-2002022622-A2 | SYNTHESIS OF 2-HYDROXYMETHYLGLUTAMIC ACID AND CONGENERS THEREOF | GEORGETOWN UNIVERSITY (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147362-A1 | Synthesis of 2-Hydroxymethylglutamic acid and congeners thereof | OGDH, FPGS, GGCT | GABRR1 1607/4885ARG1 2961/4885ARG2 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.