Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446853 | 0.81 | GABRR1 (0.40) | GABRR1CYP1A2ENPEPLTA4HFOLH1 | |
| SCHEMBL25660925 | 0.79 | GABRR1 (0.46) | GABRR1CYP1A2ENPEPLTA4HFOLH1 | |
| SCHEMBL10879775 | 0.79 | GABRR1 (0.46) | GABRR1CYP1A2ENPEPLTA4HFOLH1 | |
| SCHEMBL2629341 | 0.77 | GABRR1 (0.39) | GABRR1CYP1A2ENPEPACE2FOLH1 | |
| SCHEMBL10047547 | 0.77 | GABRR1 (0.39) | GABRR1CYP1A2ENPEPACE2FOLH1 | |
| SCHEMBL1301353 | 0.77 | CYP1A2 (0.48) | GABRR1CYP1A2ENPEPACE2LTA4H | |
| SCHEMBL10443300 | 0.76 | GABRR1 (0.43) | GABRR1CYP1A2ENPEPLTA4HFOLH1 | |
| SCHEMBL1300782 | 0.76 | GABRR1 (0.43) | GABRR1CYP1A2ENPEPLTA4HFOLH1 | |
| SCHEMBL10498366 | 0.76 | GABRR1 (0.43) | GABRR1CYP1A2ENPEPLTA4HFOLH1 | |
| SCHEMBL17198278 | 0.76 | GABRR1 (0.38) | GABRR1CYP1A2ENPEPACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147684-A1 | Diagnostic Agents Selective Against Metalloproteases | Bracco Imaging S.p.A (IT) | 2010-01-27 | — | — | EP | disclosed |