Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014599 | 0.94 | ALDH1A1 (0.36) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13013597 | 0.90 | TDP1 (0.42) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13013693 | 0.84 | ALOX15 (0.34) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL14878827 | 0.81 | ALDH1A1 (0.36) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13014615 | 0.80 | CYP19A1 (0.32) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13013664 | 0.79 | TDP1 (0.38) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13014888 | 0.77 | KDM4E (0.38) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL4311640 | 0.75 | TDP1 (0.44) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13014954 | 0.74 | KDM4E (0.35) | ALOX15HSD17B10ALDH1A1GAAUSP2 | |
| SCHEMBL13013695 | 0.72 | KDM4E (0.33) | ALOX15HSD17B10ALDH1A1GAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258683-A1 | Bisazo compounds | Clariant International Ltd. (CH) | 2010-12-08 | — | — | EP | disclosed |
| WO-2010130382-A1 | BISAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130377-A2 | BISAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251322-A1 | Bisazo compounds | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251385-A1 | Pyrazolone bisazo dyes | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2085429-A1 | Basic bisazo compounds | CLARIANT INTERNATIONAL LTD. (CH) | 2009-08-05 | — | — | EP | disclosed |