Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772133 | 0.92 | KCNH2 (0.52) | KCNH2SLC2A1 | |
| SCHEMBL3770941 | 0.82 | KCNH2 (0.60) | KCNH2SLC2A1MEN1KMT2A | |
| SCHEMBL3771627 | 0.82 | KCNH2 (0.59) | KCNH2SLC2A1MEN1KMT2A | |
| SCHEMBL3780492 | 0.81 | KCNH2 (0.41) | KCNH2SLC2A1 | |
| SCHEMBL3773354 | 0.81 | SLC2A1 (0.51) | KCNH2SLC2A1 | |
| SCHEMBL6111528 | 0.81 | SLC2A1 (0.51) | KCNH2SLC2A1 | |
| SCHEMBL5257022 | 0.81 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5255571 | 0.81 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5436076 | 0.81 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL3774520 | 0.81 | KCNH2 (0.59) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | KCNH2 3216/4885SLC2A1 4605/4885MEN1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.