Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 6/20 | 0.49 |
| ▸ | HTR1D | P28221 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111878 | 1.00 | KCNH2 (0.59) | KCNH2SLC2A1HTR1DHTR1AHTR1B | |
| SCHEMBL3782147 | 0.94 | KCNH2 (0.59) | KCNH2SLC2A1HTR1DHTR1AHTR1B | |
| SCHEMBL5251668 | 0.90 | KCNH2 (0.74) | KCNH2SLC2A1DRD2DRD4KCNQ1 | |
| SCHEMBL5254892 | 0.90 | KCNH2 (0.74) | KCNH2SLC2A1DRD2DRD4KCNQ1 | |
| SCHEMBL3781197 | 0.89 | KCNH2 (0.47) | KCNH2SLC2A1HTR1DHTR1AHTR1B | |
| SCHEMBL3774422 | 0.89 | KCNH2 (0.48) | KCNH2HTR1DHTR1AHTR1BDRD2 | |
| SCHEMBL3802794 | 0.87 | KCNH2 (0.62) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL13014300 | 0.87 | SLC2A1 (0.55) | KCNH2SLC2A1HTR1DHTR1AHTR1B | |
| SCHEMBL3779625 | 0.86 | HTR1A (0.55) | KCNH2HTR1DHTR1AHTR1BDRD2 | |
| SCHEMBL4759561 | 0.86 | SLC2A1 (0.46) | KCNH2SLC2A1HTR1DHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | KCNH2 3216/4885SLC2A1 4605/4885HTR1D 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.