Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MYLK | Q15746 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013490 | 0.94 | ADORA3 (0.48) | ADORA3ABCC1HPGDMAPTBRD4 | |
| SCHEMBL13014278 | 0.94 | BRD4 (0.49) | ADORA3MAPTBRD4BRD2BRD3 | |
| SCHEMBL13012935 | 0.93 | ADORA3 (0.49) | ADORA3ABCC1HPGDMAPTBRD4 | |
| SCHEMBL13014020 | 0.91 | ADORA3 (0.45) | ADORA3ABCC1HPGDMAPTBRD4 | |
| SCHEMBL13013473 | 0.90 | HPGD (0.49) | ADORA3ABCC1HPGDMAPTCACNA1D | |
| SCHEMBL13014460 | 0.90 | ADORA3 (0.44) | ADORA3ABCC1HPGDMAPTBRD4 | |
| SCHEMBL13013583 | 0.89 | ADORA3 (0.46) | ADORA3ABCC1HPGDMAPTBRD4 | |
| SCHEMBL13014023 | 0.89 | ADORA3 (0.42) | ADORA3ABCC1HPGDMAPTBRD4 | |
| SCHEMBL13014002 | 0.88 | ABCC1 (0.42) | ABCC1HPGDMAPTPTAFRKDM4E | |
| SCHEMBL13014079 | 0.88 | BRD4 (0.49) | ADORA3MAPTBRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149786-A1 | PYRIDO [2, 3-D] PYRIMIDINES AS WNT ANTAGONISTS FOR TREATMENT OF CANCER AND ARTHRITIS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2010-12-29 | — | — | WO | disclosed |