Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013580 | 0.93 | SMN1; SMN2 (0.39) | ALDH1A1KDM4ETSHRNPSR1P2RX3 | |
| SCHEMBL13014273 | 0.88 | ADORA3 (0.47) | ABCC1ALDH1A1KDM4EHPGDP2RX3 | |
| SCHEMBL13013020 | 0.88 | ABCC1 (0.40) | ABCC1ALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL13013486 | 0.86 | SMN1; SMN2 (0.40) | ALDH1A1KDM4ENPSR1HPGDP2RX3 | |
| SCHEMBL13013021 | 0.83 | ABCC1 (0.41) | ABCC1ALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL13014289 | 0.83 | ALDH1A1 (0.44) | ABCC1ALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL13013490 | 0.82 | ADORA3 (0.48) | ABCC1ALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL13014278 | 0.81 | BRD4 (0.49) | ALDH1A1KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13013018 | 0.81 | MEN1 (0.39) | ALDH1A1KDM4ETSHRNPSR1HPGD | |
| SCHEMBL13012935 | 0.80 | ADORA3 (0.49) | ABCC1ALDH1A1KDM4EHPGDP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149786-A1 | PYRIDO [2, 3-D] PYRIMIDINES AS WNT ANTAGONISTS FOR TREATMENT OF CANCER AND ARTHRITIS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2010-12-29 | — | — | WO | disclosed |