Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319756 | 0.89 | PDK2 (0.40) | RXRBRXRACFTRPRF1NPC1 | |
| SCHEMBL319708 | 0.89 | RXRB (0.56) | RXRBRXRAGPBAR1RXRGGPR52 | |
| SCHEMBL16433556 | 0.87 | RXRB (0.43) | RXRBRXRACFTRGPBAR1PRF1 | |
| SCHEMBL1806024 | 0.83 | RXRA (0.38) | RXRBRXRAGPR52 | |
| SCHEMBL1806466 | 0.82 | RXRA (0.37) | RXRBRXRASMN1; SMN2 | |
| SCHEMBL1806467 | 0.82 | RXRA (0.37) | RXRBRXRA | |
| SCHEMBL1804699 | 0.81 | RXRA (0.36) | RXRBRXRA | |
| SCHEMBL3653852 | 0.81 | RXRA (0.36) | RXRBRXRA | |
| SCHEMBL1805563 | 0.79 | MEN1 (0.33) | NPC1RAB9ASMN1; SMN2RUVBL1 | |
| SCHEMBL31622456 | 0.79 | RXRA (0.41) | RXRBRXRACFTRGPBAR1PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364235-B2 | Insecticidal compounds | Synenta Crop Protection LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2018-03-08 | — | — | US | disclosed |
| US-9834546-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2017-12-05 | — | — | US | disclosed |
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2017-01-26 | — | — | US | disclosed |
| US-9493445-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2016-11-15 | — | — | US | disclosed |
| US-20150111944-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-23 | — | — | US | disclosed |
| US-8946447-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2015-02-03 | — | — | US | disclosed |
| EP-2445906-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-07-23 | — | — | EP | disclosed |
| WO-2010149506-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | RXRB 4248/4885RXRA 3976/4885CFTR 1092/4885 |
| US-20150111944-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | RXRB 4248/4885RXRA 3976/4885CFTR 1092/4885 |
| US-10364235-B2 | Insecticidal compounds | ACHE, CHRM1, NIT2 | RXRB 4248/4885RXRA 3976/4885CFTR 1092/4885 |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | RXRB 4248/4885RXRA 3976/4885CFTR 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.