Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015636 | 0.89 | CYP11B2 (0.46) | EGLN2CYP11B2GPR119ACACBRET | |
| SCHEMBL20468960 | 0.87 | CYP11B2 (0.56) | CYP11B2GPR119ACACBRETPARP1 | |
| SCHEMBL13015624 | 0.86 | CYP11B2 (0.44) | EGLN2CYP11B2GPR119ACACBRET | |
| SCHEMBL14779635 | 0.86 | CYP11B2 (0.44) | EGLN2CYP11B2GPR119ACACBRET | |
| SCHEMBL13015628 | 0.84 | EIF2AK4 (0.44) | EGLN2CYP11B2GPR119ACACBCYP11B1 | |
| SCHEMBL31640018 | 0.84 | EGLN2 (0.48) | EGLN2CYP11B2GPR119ACACBRET | |
| SCHEMBL12811249 | 0.83 | EGLN2 (0.55) | EGLN2CYP11B2GPR119RETCYP11B1 | |
| SCHEMBL11359349 | 0.83 | GPR119 (0.53) | EGLN2GPR119 | |
| SCHEMBL20510354 | 0.81 | EGLN2 (0.49) | EGLN2CYP11B2GPR119ACACBRET | |
| SCHEMBL27031070 | 0.80 | GPR119 (0.60) | EGLN2CYP11B2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147234-A1 | DIARYLAMIDE-SPIRODIAMINE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-12-23 | — | — | WO | disclosed |