Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15977725 | 0.94 | CYP11B2 (0.58) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL15977585 | 0.94 | CYP11B2 (0.58) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13016059 | 0.92 | CYP11B2 (0.62) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13658730 | 0.91 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032431 | 0.90 | CYP11B2 (0.70) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL15977824 | 0.90 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL15977600 | 0.90 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL15977518 | 0.90 | CYP11B2 (0.59) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13759440 | 0.89 | CYP2A6 (0.48) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13015737 | 0.89 | HSD17B1 (0.45) | CYP11B2CYP11B1CYP19A1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137678-A1 | ELECTRON TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | チッソ株式会社 (JP) | 2010-12-02 | — | — | WO | disclosed |