Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.36 |
| ▸ | ODC1 | P11926 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PON1 | P27169 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13016662 | 0.92 | CA12 (0.53) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016588 | 0.89 | CA12 (0.62) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016795 | 0.88 | ALDH1A1 (0.56) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016877 | 0.86 | CA12 (0.50) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016619 | 0.86 | CA12 (0.43) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016647 | 0.85 | ALDH1A1 (0.45) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016644 | 0.84 | ALDH1A1 (0.44) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016655 | 0.82 | CA12 (0.41) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016723 | 0.81 | ALDH1A1 (0.40) | CA12CA1CA7CA9CA2 | |
| SCHEMBL13016596 | 0.80 | ALDH1A1 (0.51) | CA12CA1CA7CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | TBCB, TBC1D15, TBC1D5 | CA12 4246/4885CA1 4552/4885CA7 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.