SCHEMBL13016992

SCHEMBL13016992

CBN1C(=O)c2ccc(-c3ccc4c(c3)C(=O)N(C)C4=O)cc2C1=O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.49
KDM4E B2RXH2 5/20 0.47
HSD17B10 Q99714 4/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ALOX15 P16050 1/20 0.46
APP P05067 7/20 0.45
HPGD P15428 4/20 0.45
MAPK1 P28482 1/20 0.45
CASP3 P42574 1/20 0.41
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053401 0.88 ALDH1A1 (0.59) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL92524 0.79 APP (0.57) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL10635915 0.78 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL19047110 0.78 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL18905640 0.76 KDM4E (0.59) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL7591247 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL25165799 0.73 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL25165762 0.73 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL20181630 0.73 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL13018342 0.73 ALDH1A1 (0.59) ALDH1A1HSD17B10MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100331432-A1 PROCESS FOR PRODUCING POLYIMIDE FOAM AND POLYIMIDE FOAM UBE INDUSTRIES, LTD. (JP) 2010-12-30 US disclosed
US-20100331432-A1 PROCESS FOR PRODUCING POLYIMIDE FOAM AND POLYIMIDE FOAM UBE INDUSTRIES, LTD. (JP) 2010-12-30 US disclosed