Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017640 | 0.91 | HSD17B1 (0.42) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL13017646 | 0.90 | ESR1 (0.48) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL29884153 | 0.86 | HSD17B1 (0.57) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL22127106 | 0.86 | HSD17B1 (0.57) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL13016362 | 0.85 | ESR1 (0.43) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL12983197 | 0.84 | ESR1 (0.44) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL13017628 | 0.84 | ESR1 (0.44) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL18904924 | 0.83 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL24618933 | 0.82 | HSD17B1 (0.53) | HSD17B1HSD17B2ESR1ESR2CYP17A1 | |
| SCHEMBL22708077 | 0.82 | HSD17B1 (0.53) | HSD17B1HSD17B2ESR1ESR2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331585-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100331585-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331585-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | NR2E1, AR, ELP1 | HSD17B1 639/4885HSD17B2 878/4885ESR1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.