Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017628 | 0.95 | ESR1 (0.44) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL13017646 | 0.91 | ESR1 (0.48) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL13017640 | 0.89 | HSD17B1 (0.42) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL13017648 | 0.85 | HSD17B1 (0.47) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL13016302 | 0.84 | GPR84 (0.42) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL3783779 | 0.84 | ESR1 (0.40) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL3786155 | 0.84 | ESR1 (0.40) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL13016310 | 0.83 | ESR1 (0.41) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL20857798 | 0.82 | ESR1 (0.50) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL13016320 | 0.81 | HSD17B1 (0.41) | ESR1ESR2ALOX5HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568903-B2 | Phenanthrene derivative, and material for organic EL element | IDEMITSU KOSAN CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | LEF1, AR, NR0B1 | ESR1 44/4885ESR2 25/4885ALOX5 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.