Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017810 | 0.93 | BDKRB1 (0.53) | BDKRB1OPRK1 | |
| SCHEMBL10118681 | 0.92 | BDKRB1 (0.48) | BDKRB1KDM4EHSD17B10OPRK1 | |
| SCHEMBL13017811 | 0.91 | BDKRB1 (0.48) | BDKRB1OPRK1 | |
| SCHEMBL3440527 | 0.88 | BDKRB1 (0.45) | BDKRB1KDM4EHSD17B10 | |
| SCHEMBL3440390 | 0.85 | BDKRB1 (0.46) | BDKRB1KDM4EHSD17B10OPRK1 | |
| SCHEMBL3440332 | 0.85 | BDKRB1 (0.56) | BDKRB1OPRK1 | |
| SCHEMBL3440326 | 0.82 | BDKRB1 (0.49) | BDKRB1OPRK1 | |
| SCHEMBL3440405 | 0.82 | BDKRB1 (0.53) | BDKRB1KDM4EHSD17B10 | |
| SCHEMBL3440404 | 0.79 | BDKRB1 (0.46) | BDKRB1OPRK1 | |
| SCHEMBL3440302 | 0.79 | BDKRB1 (0.46) | BDKRB1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858618-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20090137545-A1 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137545-A1 | Compounds | ADORA2B, ABCB11, CYP11B1 | BDKRB1 6/4885KDM4E 3277/4885HSD17B10 854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.