SCHEMBL1301822

SCHEMBL1301822

CC1(C)O[C@H]([C@H](O)CO)[C@@H]([C@H](O)CO)O1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
THPO P40225 1/20 0.41
MANBA O00462 1/20 0.36
THRB P10828 1/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6676888 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL15678411 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL12018358 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL18596140 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL2756249 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL7147890 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL1984099 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL2367932 1.00 LMNA (0.41) LMNACYP1A2THPOMANBATHRB
SCHEMBL7147304 0.91 LMNA (0.38) LMNACYP1A2THPOMANBATHRB
SCHEMBL18263599 0.91 LMNA (0.38) LMNACYP1A2THPOMANBATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5709737-A AQUEOUS LIQUID VEHICLE, COLORANT, ALCOHOL ADDITIVE; SUITABLE FOR MICROWAVE DRYING PROCESSES XEROX CORPORATION (US) 1998-01-20 US claimed
US-4804789-A D-mannite derivatives as starting products for the synthesis of phospholipids MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1989-02-14 US claimed
CN-107428665-B Method for producing (meth) acrylic ester 东亚合成株式会社 2021-10-15 CN disclosed
CN-107406363-B Method for producing (meth) acrylic ester 东亚合成株式会社 2021-10-08 CN disclosed
EP-3010488-B1 STEREOSPECIFIC LIPIDS FOR LOCOREGIONAL THERAPY WITH LONG-TERM CIRCULATING STIMULI-SENSITIVE NANOCARRIER SYSTEMS THERMOSOME GmbH (DE) 2021-05-05 EP disclosed
CN-107709377-B Curable composition 东亚合成株式会社 2021-04-20 CN disclosed
CN-107709376-B Curable composition 东亚合成株式会社 2020-10-30 CN disclosed
EP-3281933-B1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO LTD (JP) 2020-08-19 EP disclosed
CN-107148410-B Cationic lipids for nucleic acid delivery 日油株式会社 2020-04-28 CN disclosed
US-10619058-B2 Curable composition TOAGOSEI CO., LTD. (JP) 2020-04-14 US disclosed
US-10611856-B2 Curable composition TOAGOSEI CO., LTD. (JP) 2020-04-07 US disclosed
WO-1994019329-A1 SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-09-01 WO disclosed
US-5298492-A Inhibitors of endopeptidase and treatment of cardiovascular disorders SCHERING CORPORATION (US) 1994-03-29 US disclosed
WO-1994003481-A1 DIAMINO ACID DERIVATIVES AS ANTIHYPERTENSIVES SCHERING CORPORATION (US) 1994-02-17 WO disclosed
EP-0222522-B1 PLATINUM COORDINATION COMPOUNDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1990-03-14 EP disclosed
US-4804789-A D-mannite derivatives as starting products for the synthesis of phospholipids MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1989-02-14 US disclosed
US-4783452-A ANTITUMOR AGENTS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1988-11-08 US disclosed
US-4734225-A ANTITUMOR AGENTS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1988-03-29 US disclosed
US-4709059-A Process for selective halogenation of primary hydroxyl groups THE DOW CHEMICAL COMPANY (US) 1987-11-24 US disclosed
EP-0222522-A2 Platinum coordination compounds JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1987-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10611856-B2 Curable composition ACR, KAT2B, KAT5 LMNA 618/4885CYP1A2 4521/4885THPO 538/4885
US-10619058-B2 Curable composition ZMYND8, AZI2, KAT2A LMNA 568/4885CYP1A2 3885/4885THPO 1034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.