Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074124 | 0.92 | KDM4E (0.60) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL16819097 | 0.91 | KDM4E (0.55) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL8739918 | 0.89 | KDM4E (0.47) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL22260174 | 0.89 | KDM4E (0.47) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL17933300 | 0.88 | KDM4E (0.53) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL19342638 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL13368077 | 0.86 | KDM4E (0.50) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL18627690 | 0.86 | KDM4E (0.53) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL16268823 | 0.86 | KDM4E (0.47) | KDM4EL3MBTL1ATMPGRRORA | |
| SCHEMBL21077110 | 0.85 | KDM4E (0.50) | KDM4EL3MBTL1ATMPGRRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546505-B2 | Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-10-01 | — | — | US | disclosed |
| US-20100331509-A1 | Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331509-A1 | Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials | OCIAD1, HPD, OXA1L | KDM4E 4260/4885L3MBTL1 1007/4885ATM 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.