SCHEMBL10074124

SCHEMBL10074124

CCc1ccc2c(c1)c1ccccc1n2-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
ATM Q13315 1/20 0.60
PGR P06401 3/20 0.47
RORA P35398 1/20 0.47
RORC P51449 1/20 0.47
RORB Q92753 1/20 0.47
MAPK8 P45983 2/20 0.45
MAPK1 P28482 2/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 3/20 0.42
TP53 P04637 2/20 0.42
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 2/20 0.41
HTT P42858 1/20 0.41
HBB P68871 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16819097 0.95 KDM4E (0.55) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL13368077 0.95 KDM4E (0.50) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL18627690 0.94 KDM4E (0.53) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL13018686 0.92 KDM4E (0.48) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL13542510 0.91 KDM4E (0.49) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL16268823 0.90 KDM4E (0.47) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL17017083 0.90 KDM4E (0.60) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL19075299 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL8086611 0.88 KDM4E (0.49) KDM4EL3MBTL1ATMPGRRORA
SCHEMBL25909682 0.87 KDM4E (0.56) KDM4EL3MBTL1ATMPGRRORA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185330-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-08-16 EP disclosed
US-11638390-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-04-25 US disclosed
EP-3826080-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2021-05-26 EP disclosed
US-20210066613-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2021-03-04 US disclosed
WO-2020212296-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-10-22 WO disclosed
WO-2020182779-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-17 WO disclosed
US-20200119287-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2020-04-16 US disclosed
EP-3174885-B1 2,9-FUNCTIONALIZED BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES AS HOSTS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO (JP) 2019-10-02 EP disclosed
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
EP-2725080-B1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2018-01-24 EP disclosed
US-20160028016-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-9054323-B2 Secondary hole transporting layer with diarylamino-phenyl-carbazole compounds UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-20150021555-A1 DONOR-ACCEPTOR COMPOUNDS WITH NITROGEN CONTAINING HETEROPOLYAROMATICS AS THE ELECTRON ACCEPTOR UNIVERSAL DISPLAY CORPORATION 2015-01-22 US disclosed
US-8664393-B2 Ruthenium complex-based photosensitizer dyes for dye-sensitized solar cells NATIONAL CHIAO TUNG UNIVERSITY (TW) 2014-03-04 US disclosed
US-20130241401-A1 SECONDARY HOLE TRANSPORTING LAYER WITH DIARYLAMINO-PHENYL-CARBAZOLE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2013-09-19 US disclosed
US-20120296086-A1 RUTHENIUM COMPLEX-BASED PHOTOSENSITIZER DYES FOR DYE-SENSITIZED SOLAR CELLS NATIONAL CHIAO TUNG UNIVERSITY (TW) 2012-11-22 US disclosed
WO-2012020327-A1 BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS BASF SE (DE) 2012-02-16 WO disclosed
US-7960566-B2 Anthracene derivative and light-emitting devices, electronic devices, and lighting device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-06-14 US disclosed
US-20100099890-A1 ANTHRACENE DERIVATIVE AND LIGHT-EMITTING DEVICES, ELECTRONIC DEVICES, AND LIGHTING DEVICE USING THE ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-04-22 US disclosed
WO-2008140657-A1 ORGANOMETALLIC COMPOUNDS HAVING HOST AND DOPANT FUNCTIONALITIES UNIVERSAL DISPLAY CORPORATION (US) 2008-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 KDM4E 225/4885L3MBTL1 1263/4885ATM 3092/4885
US-20130241401-A1 SECONDARY HOLE TRANSPORTING LAYER WITH DIARYLAMINO-PHENYL-CARBAZOLE COMPOUNDS SLC29A2, SLC29A1, ARNT KDM4E 3847/4885L3MBTL1 893/4885ATM 3572/4885
US-20200119287-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CLTB, CYBA KDM4E 3854/4885L3MBTL1 526/4885ATM 1928/4885
US-20210066613-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CYBA, NDUFV3 KDM4E 4617/4885L3MBTL1 1409/4885ATM 2079/4885
US-20100099890-A1 ANTHRACENE DERIVATIVE AND LIGHT-EMITTING DEVICES, ELECTRONIC DEVICES, AND LIGHTING DEVICE USING THE ANTHRACENE DERIVATIVE SUN2, CRY2, XPOT KDM4E 1271/4885L3MBTL1 1129/4885ATM 468/4885
US-11638390-B2 Composition of matter for use in organic light-emitting diodes CRY2, CLTB, CYBA KDM4E 3854/4885L3MBTL1 526/4885ATM 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.