Sugi Predict

Sugi Predict / Compounds / Iosarcol

Iosarcol

Iosarcol

SCHEMBL1301899

CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)N(C)CC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)c1I.COCC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.74
▸ CYP2C19 P33261 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iopromide SCHEMBL29632300 0.86 LMNA (1.00) LMNACYP2C19HIF1A
Iopromide SCHEMBL8845234 0.86 LMNA (1.00) LMNACYP2C19HIF1A
Iopromide SCHEMBL24546 0.86 LMNA (1.00) LMNACYP2C19HIF1A
SCHEMBL9009184 0.83 LMNA (0.93) LMNACYP2C19HIF1A
SCHEMBL14864477 0.82 LMNA (0.91) LMNACYP2C19HIF1A
SCHEMBL18931642 0.82 LMNA (0.91) LMNACYP2C19HIF1A
SCHEMBL13309814 0.82 LMNA (0.90) LMNACYP2C19HIF1A
Iopromide SCHEMBL19030790 0.81 LMNA (0.75) LMNACYP2C19HIF1ASMN1; SMN2
Iohexol SCHEMBL9807215 0.81 LMNA (0.84) LMNACYP2C19HIF1A
Iosarcol SCHEMBL29473413 0.81 SMN1; SMN2 (0.55) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180104185-A1 LIQUID COMPOSITIONS CAPABLE OF FOAMING AND INCLUDING ACTIVE AGENTS, AND METHODS FOR MAKING OR DEVELOPING SAME MIKA PHARMA GMBH 2018-04-19 — — US disclosed
US-9693956-B2 Liquid compositions capable of foaming and including active agents, and methods for making or developing same MIKA PHARMA GMBH 2017-07-04 — — US disclosed
US-20160022579-A1 Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same MIKA PHARMA GMBH 2016-01-28 — — US disclosed
US-9005626-B2 Liquid compositions capable of foaming and including active agents, and methods for making or developing same MIKA PHARMA GMBH (DE) 2015-04-14 — — US disclosed
US-20110269704-A1 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FUR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-11-03 — — US disclosed
US-20110059117-A1 Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same MIKA PHARMA GMBH (DE) 2011-03-10 — — US disclosed