Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571476 | 0.87 | USP2 (0.48) | PLA2G2CALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3184286 | 0.85 | TAS1R3 (0.43) | PLA2G2CALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3184278 | 0.85 | TAS1R3 (0.43) | PLA2G2CALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL11404747 | 0.84 | KDM4E (0.37) | PLA2G2CALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL15723450 | 0.83 | TAS1R3 (0.37) | ALDH1A1LMNATHRBTAS1R3TAS1R1 | |
| SCHEMBL19861654 | 0.83 | ALDH1A1 (0.35) | PLA2G2CALDH1A1LMNATAS1R3TAS1R1 | |
| SCHEMBL12064029 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL12064309 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL12064041 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL8061894 | 0.81 | ALDH1A1 (0.39) | PLA2G2CALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858388-B2 | MS based peptide and protein sequencing via reactions of lysine residues with peroxycarbonate compounds | VANDERBILT UNIVERSITY (US) | 2010-12-28 | — | — | US | disclosed |
| US-7858388-B2 | MS based peptide and protein sequencing via reactions of lysine residues with peroxycarbonate compounds | VANDERBILT UNIVERSITY (US) | 2010-12-28 | — | — | US | disclosed |