Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146531 | 0.95 | CYP2C19 (0.37) | CYP2C19APPCNR2CNR1ALDH1A1 | |
| SCHEMBL25956477 | 0.94 | CYP2C19 (0.36) | CYP2C19APPCNR2CNR1ALDH1A1 | |
| SCHEMBL19774529 | 0.93 | ALDH1A1 (0.37) | CYP2C19ALDH1A1TDP1TSHRACHE | |
| SCHEMBL13700667 | 0.90 | ALDH1A1 (0.42) | CYP2C19APPALDH1A1TDP1KDM4E | |
| SCHEMBL16158447 | 0.90 | ALDH1A1 (0.42) | CYP2C19APPALDH1A1TDP1KDM4E | |
| SCHEMBL15043942 | 0.90 | ALDH1A1 (0.42) | CYP2C19APPALDH1A1TDP1KDM4E | |
| SCHEMBL10062652 | 0.89 | ALDH1A1 (0.35) | CYP2C19ALDH1A1TDP1KDM4ECYP1A2 | |
| SCHEMBL22108898 | 0.88 | ALDH1A1 (0.33) | CYP2C19ALDH1A1TSHR | |
| SCHEMBL13815195 | 0.87 | CYP2C19 (0.33) | CYP2C19APP | |
| SCHEMBL14048724 | 0.86 | ALDH1A1 (0.35) | CYP2C19APPALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10635009-B2 | Electrophotographic photosensitive member, process cartridge, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-28 | — | — | US | disclosed |
| EP-3288094-A1 | LIGHT EMITTING ELEMENT AND COMPOSITION USED IN SAID LIGHT EMITTING ELEMENT | Sumitomo Chemical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |
| EP-3260438-A1 | DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME | LG Chem, Ltd. (KR) | 2017-12-27 | — | — | EP | disclosed |
| WO-2017089123-A1 | BORONDIFLUORIDE COMPLEXES OF CURCOMINOID COMPOUNDS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX MARSEILLE (FR) | 2017-06-01 | — | — | WO | disclosed |
| US-20170133589-A1 | FLUORENE DERIVATIVE AND USE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| EP-2262025-A2 | Organic electroluminescent device | TDK Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |
| WO-2008133459-A1 | NEW DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2008-11-06 | — | — | WO | disclosed |
| US-7345141-B2 | Luminescent material and a transport material (e.g., an electron transport material, a hole transport material, etc.) for use in an organic electroluminescent (EL) element which can be used for a display section, etc., of an information apparatus, such an a computer, or an electronics product, television | SHARP KABUSHIKI KAISHA (JP) | 2008-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170133589-A1 | FLUORENE DERIVATIVE AND USE THEREOF | AFF1, AFF2, NR0B2 | CYP2C19 112/4885APP 2798/4885CNR2 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.