Ampyrone

Ampyrone

SCHEMBL130194

CCNc1cccc(C)c1.Cc1c(N)c(=O)n(-c2ccccc2)n1C.O=S(=O)(O)CC(O)C[Na]

nearest known ligand 0.47

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
PTGS2 P35354 1/20 0.47
ALDH1A1 P00352 5/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 1/20 0.41
HTT P42858 2/20 0.39
PTGS1 P23219 1/20 0.39
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
HSD17B10 Q99714 1/20 0.36
F2 P00734 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5569666 0.81 MAPT (0.44) ALDH1A1MAPTGAAHTTSMN1; SMN2
Ampyrone SCHEMBL5973541 0.78 BCHE (0.47) BCHEPTGS2ALDH1A1MAPTGAA
Ampyrone SCHEMBL27868612 0.72 BCHE (0.79) BCHEPTGS2ALDH1A1MAPTPTGS1
Ampyrone SCHEMBL28606780 0.72 BCHE (0.84) BCHEPTGS2ALDH1A1MAPTPTGS1
SCHEMBL27877781 0.70 MAPT (0.46) ALDH1A1MAPTGAAHTTSMN1; SMN2
SCHEMBL9289731 0.70 HTT (0.36) HTT
Ampyrone SCHEMBL10711697 0.69 BCHE (0.82) BCHEPTGS2ALDH1A1MAPTGAA
SCHEMBL17035245 0.68 BCHE (0.71) BCHEPTGS2ALDH1A1MAPTSMN1; SMN2
Ampyrone SCHEMBL18159502 0.68 BCHE (1.00) BCHEPTGS2ALDH1A1MAPTGAA
Ampyrone SCHEMBL11674586 0.68 BCHE (1.00) BCHEPTGS2ALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130171675-A1 MEASURING DEVICE AND MEASURING METHOD TOYOBO CO., LTD. (JP) 2013-07-04 US disclosed
WO-2012163361-A1 METHOD AND SYSTEM FOR IDENTIFICATION OF PHYSIOLOGICAL IMBALANCE IN AN ANIMAL AARHUS UNIVERSITET (DK) 2012-12-06 WO disclosed
US-8206944-B2 Dry stick device construction and method for determining an analyte in a sample using said dry stick device LATTEC I/S (DK) 2012-06-26 US disclosed
EP-1982182-B1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE LATTEC I S (DK) 2012-03-07 EP disclosed
US-20110039290-A1 NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE LATTEC I/S (DK) 2011-02-17 US disclosed
EP-1982182-A1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE Lattec I/S (DK) 2008-10-22 EP disclosed
WO-2007082544-A1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE LATTEC I/S (DK) 2007-07-26 WO disclosed