Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127387 | 0.81 | GLA (0.44) | ALDH1A1HTTHSD17B10POLBGLA | |
| SCHEMBL29742941 | 0.80 | GLA (0.46) | ALDH1A1HSD17B10POLBGLASMN1; SMN2 | |
| SCHEMBL246863 | 0.80 | GLA (0.44) | ALDH1A1HTTHSD17B10POLBGLA | |
| Water SCHEMBL22611645 | 0.79 | GLA (0.43) | ALDH1A1HTTHSD17B10POLBGLA | |
| Water SCHEMBL29402591 | 0.79 | GLA (0.46) | ALDH1A1HSD17B10POLBGLASMN1; SMN2 | |
| Ampyrone SCHEMBL130194 | 0.78 | BCHE (0.47) | BCHEPTGS2ALDH1A1HTTPTGS1 | |
| Benzoquinone SCHEMBL1665500 | 0.78 | GLA (0.41) | ALDH1A1HTTHSD17B10GAAPOLB | |
| SCHEMBL3255714 | 0.78 | GLA (0.42) | ALDH1A1HTTHSD17B10POLBGLA | |
| Ampyrone SCHEMBL10870386 | 0.76 | BCHE (0.73) | BCHEPTGS2ALDH1A1PTGS1HSD17B10 | |
| Ampyrone SCHEMBL3178309 | 0.73 | BCHE (0.56) | BCHEPTGS2ALDH1A1HTTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921198-B1 | METHOD FOR ENZYMATICALLY ASSAYING SACCHARIFICATION PROTEIN | ARKRAY INC (JP) | 2006-07-19 | — | — | EP | disclosed |
| EP-0921198-A1 | METHOD FOR ENZYMATICALLY ASSAYING SACCHARIFICATION PROTEIN | Kyoto Daiichi Kagaku Co., Ltd. (JP) | 1999-06-09 | — | — | EP | disclosed |