Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.77 |
| ▸ | HTR1A | P08908 | 7/20 | 0.67 |
| ▸ | HTR7 | P34969 | 6/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706541 | 0.88 | KCNH2 (0.79) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL4525555 | 0.88 | KCNH2 (1.00) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL1706148 | 0.84 | KCNH2 (0.68) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL2214111 | 0.84 | KCNH2 (0.86) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL7270516 | 0.84 | HTR1A (0.72) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL30767216 | 0.83 | KCNH2 (0.90) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL3187888 | 0.83 | KCNH2 (0.74) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL7484502 | 0.82 | KCNH2 (0.83) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL13875118 | 0.82 | KCNH2 (0.83) | KCNH2HTR1AHTR7DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7658247 | 0.82 | KCNH2 (0.88) | KCNH2HTR1AHTR7DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261259-A1 | Immunoassay for N-(3-chlorophenyl)piperazine-based anti-depressants | Randox Laboratories Ltd. (GB) | 2010-12-15 | — | — | EP | disclosed |