Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.68 |
| ▸ | HTR1A | P08908 | 5/20 | 0.60 |
| ▸ | HTR7 | P34969 | 5/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759929 | 0.95 | KCNH2 (0.64) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL10763277 | 0.91 | HTR1A (0.65) | KCNH2HTR1AHTR7HTR2A | |
| SCHEMBL1375341 | 0.86 | ALDH1A1 (0.65) | HTR1AHTR7 | |
| SCHEMBL1374761 | 0.86 | ALDH1A1 (0.65) | HTR1AHTR7 | |
| SCHEMBL13019474 | 0.84 | KCNH2 (0.77) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL4932317 | 0.84 | KCNH2 (0.53) | KCNH2HTR1AHTR7DRD2DRD4 | |
| SCHEMBL1706541 | 0.83 | KCNH2 (0.79) | KCNH2HTR1AHTR7DRD2HTR2A | |
| SCHEMBL10759276 | 0.83 | TSHR (0.61) | KCNH2HTR1AHTR7 | |
| SCHEMBL10759040 | 0.83 | DRD4 (0.47) | KCNH2HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL4525555 | 0.83 | KCNH2 (1.00) | KCNH2HTR1AHTR7DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440938-B1 | mCPP IMMUNOASSAY | RANDOX LAB LTD (GB) | 2015-03-11 | — | — | EP | disclosed |
| EP-2261259-B1 | Immunoassay for N-(3-chlorophenyl)piperazine-based anti-depressants | RANDOX LAB LTD (GB) | 2014-07-30 | — | — | EP | disclosed |
| US-8476029-B2 | MCPP immunoassay | RANDOX LABORATORIES LTD (GB) | 2013-07-02 | — | — | US | disclosed |
| US-20120135434-A1 | MCPP IMMUNOASSAY | RANDOX LABORATORIES LTD. (UK) | 2012-05-31 | — | — | US | disclosed |
| EP-2440938-A1 | mCPP IMMUNOASSAY | Randox Laboratories Ltd. (GB) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010142974-A1 | mCPP IMMUNOASSAY | RANDOX LABORATORIES LTD (GB) | 2010-12-16 | — | — | WO | disclosed |
| EP-2261259-A1 | Immunoassay for N-(3-chlorophenyl)piperazine-based anti-depressants | Randox Laboratories Ltd. (GB) | 2010-12-15 | — | — | EP | disclosed |