Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509522 | 0.85 | AR (0.66) | ARSLC6A4KDM1AUSP2MAPT | |
| SCHEMBL29490258 | 0.85 | AR (0.66) | ARSLC6A4KDM1AUSP2MAPT | |
| Ammonia Solution, Strong SCHEMBL3939793 | 0.80 | AR (0.57) | ARSLC6A4TRPV4KDM1AUSP2 | |
| SCHEMBL6162573 | 0.80 | AR (0.47) | ARSLC6A4TRPV4ALDH1A1LRRK2 | |
| SCHEMBL14805912 | 0.80 | AR (0.55) | ARSLC6A4TRPV4NR3C1PGR | |
| SCHEMBL21501064 | 0.79 | AR (0.60) | ARSLC6A4KDM1AUSP2MAPT | |
| SCHEMBL14805812 | 0.79 | TRPV4 (0.42) | ARSLC6A4TRPV4NR3C1PGR | |
| SCHEMBL6165493 | 0.79 | AR (0.40) | ARSLC6A4TRPV4KDM1AMAPT | |
| SCHEMBL8119447 | 0.78 | AR (0.58) | ARSLC6A4KDM1AUSP2MAPT | |
| SCHEMBL12593793 | 0.77 | AR (0.50) | ARSLC6A4KDM1AUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | AR 1946/4885SLC6A4 1912/4885TRPV4 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.