Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.54 |
| ▸ | SRC | P12931 | 9/20 | 0.54 |
| ▸ | EGFR | P00533 | 9/20 | 0.54 |
| ▸ | HCK | P08631 | 7/20 | 0.54 |
| ▸ | KDR | P35968 | 7/20 | 0.54 |
| ▸ | FYN | P06241 | 3/20 | 0.54 |
| ▸ | BTK | Q06187 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | LYN | P07948 | 2/20 | 0.54 |
| ▸ | BLK | P51451 | 2/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | YES1 | P07947 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | FGR | P09769 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788008 | 0.83 | SRC (0.62) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13064038 | 0.81 | ABL1 (0.48) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL3778669 | 0.80 | SRC (0.58) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13064031 | 0.80 | SRC (0.58) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13064032 | 0.78 | NUDT14 (0.49) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL3779241 | 0.77 | SRC (0.55) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13019941 | 0.77 | SRC (0.60) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13019903 | 0.76 | SRC (0.58) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13019694 | 0.75 | PIK3CD (0.72) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL13019691 | 0.75 | PIK3CD (0.72) | ABL1SRCEGFRHCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | ABL1 1725/4885SRC 1332/4885EGFR 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.