Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.74 |
| ▸ | ABL1 | P00519 | 12/20 | 0.74 |
| ▸ | SRC | P12931 | 12/20 | 0.74 |
| ▸ | EGFR | P00533 | 11/20 | 0.74 |
| ▸ | HCK | P08631 | 11/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.74 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.74 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.74 |
| ▸ | PRKDC | P78527 | 11/20 | 0.74 |
| ▸ | MTOR | P42345 | 10/20 | 0.74 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.74 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.74 |
| ▸ | RET | P07949 | 5/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | LYN | P07948 | 2/20 | 0.55 |
| ▸ | BTK | Q06187 | 2/20 | 0.55 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13020103 | 1.00 | KDR (0.74) | KDRABL1SRCEGFRHCK | |
| SCHEMBL1319895 | 0.91 | KDR (0.71) | KDRABL1SRCEGFRHCK | |
| SCHEMBL1319000 | 0.91 | KDR (0.71) | KDRABL1SRCEGFRHCK | |
| SCHEMBL1318998 | 0.91 | KDR (0.71) | KDRABL1SRCEGFRHCK | |
| SCHEMBL13019691 | 0.85 | PIK3CD (0.72) | KDRABL1SRCEGFRHCK | |
| SCHEMBL13019694 | 0.85 | PIK3CD (0.72) | KDRABL1SRCEGFRHCK | |
| SCHEMBL1320199 | 0.84 | KDR (0.63) | KDRABL1SRCEGFRHCK | |
| SCHEMBL1320201 | 0.84 | KDR (0.63) | KDRABL1SRCEGFRHCK | |
| SCHEMBL1321276 | 0.84 | KDR (0.63) | KDRABL1SRCEGFRHCK | |
| SCHEMBL24096496 | 0.84 | PIK3CD (0.61) | KDRABL1SRCEGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | KDR 4598/4885ABL1 1725/4885SRC 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.