SCHEMBL1302194

SCHEMBL1302194

CCCCCCCCC=CCCCCCCCCCCO

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.68
HSD17B10 Q99714 3/20 0.68
KMT2A Q03164 3/20 0.68
MEN1 O00255 2/20 0.68
ALDH1A1 P00352 1/20 0.68
TSHR P16473 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.63
FAAH O00519 4/20 0.58
TRPV1 Q8NER1 1/20 0.58
TERT O14746 3/20 0.56
CYP1A2 P05177 2/20 0.56
MAPT P10636 2/20 0.56
CYP2C19 P33261 2/20 0.56
BLM P54132 2/20 0.56
FABP4 P15090 2/20 0.56
PTPN1 P18031 2/20 0.56
PPARG P37231 2/20 0.56
PPARD Q03181 2/20 0.56
PPARA Q07869 2/20 0.56
GMNN O75496 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5039239 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL833160 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL5044800 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL5361747 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL22616793 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL24450559 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL5040020 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL2933864 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL21065749 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL4881870 1.00 LMNA (0.68) LMNAHSD17B10KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160175209-A1 COMPOSITION FOR ENHANCING HAIR FIBER PROPERTIES THE PROCTER & GAMBLE COMPANY 2016-06-23 US claimed
US-20150297505-A1 ANTI-AGING COSMETIC COMPOSITION INCLUDING LIPID-SOLUBLE FRACTION OF BEE VENOM AND METHODS FOR PREPARING THE SAME WISSEN CO., LTD. (KR) 2015-10-22 US claimed
EP-2923693-A1 ANTI-AGING COSMETIC COMPOSITION COMPRISING FAT-SOLUBLE FRACTIONS OF BEE VENOM, AND METHOD FOR PREPARING SAME Wissen Co., Ltd (KR) 2015-09-30 EP claimed
US-8987531-B2 Syntheses of Z-olefin-containing lepidopteran insect pheromones CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2015-03-24 US claimed
EP-2838359-A1 SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES California Institute of Technology (US) 2015-02-25 EP claimed
WO-2014140392-A1 INTEGRATED METHOD OF OBTAINING MONOUNSATURATED ALCOHOLS, BIODIESEL AND BIODEGRADABLE PRODUCTS FROM JOJOBA OIL UNIVERSIDAD COMPLUTENSE DE MADRID (ES) 2014-09-18 WO claimed
US-8563015-B2 Cosmetic composition combining an ethylenic ester of trans configuration and a hydrocarbon wax L'OREAL (FR) 2013-10-22 US claimed
WO-2013134192-A1 SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-09-12 WO claimed
US-20130231499-A1 SYNTHESIS OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES CALIFORNIA INSTITUTE OF TECHNOLOGY 2013-09-05 US claimed
US-20120128763-A1 LUBRICANT FOR THE OCULAR SURFACE MELBJ HOLDINGS, LLC 2012-05-24 US claimed
EP-1550431-B1 Cosmetic composition with an ethylenic ester in trans-conformation together with a hydrocarbon wax OREAL (FR) 2011-07-27 EP claimed
EP-1850670-A4 FORMULATIONS USEFUL FOR THE TREATMENT OF VARICELLA ZOSTER VIRUS INFECTIONS AND METHODS FOR THE USE THEREOF VERBISCAR ANTHONY J (US) 2008-08-06 EP claimed
EP-1850670-A1 FORMULATIONS USEFUL FOR THE TREATMENT OF VARICELLA ZOSTER VIRUS INFECTIONS AND METHODS FOR THE USE THEREOF Verbiscar, Anthony, J. (US) 2007-11-07 EP claimed
EP-1727565-A2 LUBRICANT FOR THE OCULAR SURFACE Melbj Holdings, LLC (US) 2006-12-06 EP claimed
WO-2006112938-A1 FORMULATIONS USEFUL FOR THE TREATMENT OF VARICELLA ZOSTER VIRUS INFECTIONS AND METHODS FOR THE USE THEREOF VERBISCAR ANTHONY J (US) 2006-10-26 WO claimed
WO-2006004577-A2 LUBRICANT FOR THE OCULAR SURFACE MELBJ HOLDINGS, LLC (US) 2006-01-12 WO claimed
US-20050226833-A1 Cosmetic composition combining an ethylenic ester of trans configuration and a hydrocarbon wax L'OREAL (FR) 2005-10-13 US claimed
US-20050203187-A1 Formulations useful for the treatment of varicella zoster virus infections and methods for the use thereof VERBISCAR ANTHONY J (US) 2005-09-15 US claimed
US-20050202097-A1 Lubricant for the ocular surface MELBJ HOLDINGS, LLC, FLORIDA 2005-09-15 US claimed
US-6703052-B2 FATTY ALCOHOL; HYDROGENOLYSIS OF OIL USING HYDRIDE REDUCING AGENT VERBISCAR ANTHONY J (US) 2004-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160175209-A1 COMPOSITION FOR ENHANCING HAIR FIBER PROPERTIES PHOSPHO1, SGMS1, SGMS2 LMNA 375/4885HSD17B10 415/4885KMT2A 2058/4885
US-20130231499-A1 SYNTHESIS OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES ZYX, OSBP, ZDHHC7 LMNA 4429/4885HSD17B10 770/4885KMT2A 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.