SCHEMBL13022786

SCHEMBL13022786

COc1ccccc1N1c2ccccc2[S+]([O-])c2c1oc1ccc(C)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
THRB P10828 1/20 0.38
TP53 P04637 3/20 0.38
MAPT P10636 5/20 0.38
NPC1 O15118 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 3/20 0.36
HTT P42858 2/20 0.36
CD74 P04233 1/20 0.36
MIF P14174 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022070 0.95 MEN1 (0.41) MEN1KMT2ATHRBTP53MAPT
SCHEMBL13023846 0.88 MAPT (0.34) MEN1KMT2ATHRBMAPTNPC1
SCHEMBL13022779 0.86 KDM4E (0.35) TP53MAPTNPC1HSD17B10KDM4E
SCHEMBL13022798 0.83 KDM4E (0.40) MEN1KMT2ATP53MAPTNPC1
SCHEMBL13022812 0.82 KDM4E (0.34) TP53MAPTNPC1HSD17B10KDM4E
SCHEMBL13022063 0.81 KDM4E (0.33) TP53MAPTHSD17B10KDM4EHPGD
SCHEMBL13023899 0.80 MEN1 (0.34) MEN1KMT2ATHRBTP53MAPT
SCHEMBL13022817 0.79 KDM4E (0.32) TP53MAPTHSD17B10KDM4EHPGD
SCHEMBL13023828 0.79 LMNA (0.34) MAPTKDM4ERAB9ASMN1; SMN2LMNA
SCHEMBL13022803 0.79 NPSR1 (0.37) MEN1KMT2ATP53MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MEN1 725/4885KMT2A 2070/4885THRB 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.