SCHEMBL1302280

SCHEMBL1302280

C=CC(=O)OCCS(=O)(=O)O.[LiH]

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.54
ALDH1A1 P00352 4/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HPGD P15428 1/20 0.48
THRB P10828 2/20 0.41
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTGS1 P23219 1/20 0.31
PDE4A P27815 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A6 P31641 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16327 0.98 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL1254117 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL165903 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8861475 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5053935 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8861451 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6916022 0.90 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8942520 0.90 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2457988 0.88 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27954421 0.87 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024774-A Polyelectrolyte gel, preparation method and application thereof 清华大学 2023-11-10 CN claimed
CN-117024774-A Polyelectrolyte gel, preparation method and application thereof 清华大学 2023-11-10 CN disclosed
US-9217052-B2 Copolymer NIPPON SODA CO., LTD. (JP) 2015-12-22 US disclosed
CN-105068377-A Coloring composition for color filter, color filter and display element JSR CORP 2015-11-18 CN disclosed
CN-102221779-B Color composition for color filter, color filter and color liquid crystal display device JSR CO., LTD. (JP) 2015-08-26 CN disclosed
US-9115239-B2 Copolymer NIPPON SODA CO., LTD. (JP) 2015-08-25 US disclosed
CN-102221778-B Coloring composition for color filter, color filter and display element JSR CORP. (JP) 2015-08-19 CN disclosed
CN-102869693-B Novel copolymer NIPPON SODA CO 2015-04-15 CN disclosed
EP-2559715-B1 NOVEL COPOLYMER NIPPON SODA CO (JP) 2015-02-25 EP disclosed
CN-102958964-B Copolymer NIPPON SODA CO 2015-02-25 CN disclosed
EP-2559715-A1 NOVEL COPOLYMER Nippon Soda Co., Ltd. (JP) 2013-02-20 EP disclosed
US-20130023628-A1 NOVEL COPOLYMER NIPPON SODA CO., LTD. (JP) 2013-01-24 US disclosed
CN-102869693-A Novel copolymer NIPPON SODA CO 2013-01-09 CN disclosed
EP-2387866-A1 ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION 3M Innovative Properties Company (US) 2011-11-23 EP disclosed
US-20110268950-A1 Electromagnetic Wave Shielding Gel-Like Composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-03 US disclosed
CN-102221779-A Coloring composition applied in color filter, color filter and colored liquid crystal display element JSR CORP 2011-10-19 CN disclosed
CN-102221778-A Coloring composition for color filter, color filter and display element JSR CORP 2011-10-19 CN disclosed
US-8038066-B2 Laser scanner with deformable lens HAND HELD PRODUCTS, INC. (US) 2011-10-18 US disclosed
CN-102066486-A Gel composition, method for preparing the same, and impact-resistant absorbing material using the same 3M INNOVATIVE PROPERTIES CO 2011-05-18 CN disclosed
WO-2010083075-A1 ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-07-22 WO disclosed