SCHEMBL165903

SCHEMBL165903

C=CC(=O)OCCS(=O)(=O)O.[NaH]

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.54
ALDH1A1 P00352 4/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HPGD P15428 1/20 0.48
THRB P10828 2/20 0.41
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTGS1 P23219 1/20 0.31
PDE4A P27815 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A6 P31641 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16327 0.98 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1302280 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8861475 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8861451 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL1254117 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5053935 0.96 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8942520 0.90 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6916022 0.90 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL474181 0.88 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27954421 0.87 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024774-A Polyelectrolyte gel, preparation method and application thereof 清华大学 2023-11-10 CN claimed
CN-113056526-B Aqueous coating composition 巴斯夫欧洲公司 2023-04-14 CN claimed
US-20210388195-A1 WATERBORNE COATING COMPOSITIONS BASF SE (DE) 2021-12-16 US claimed
EP-3884001-A2 WATERBORNE COATING COMPOSITIONS BASF SE (DE) 2021-09-29 EP claimed
CN-113056526-A Aqueous coating composition 巴斯夫欧洲公司 2021-06-29 CN claimed
EP-3710537-A1 FAST DRYING, HIGH BUILD, SAG-RESISTANT COMPOSITIONS, COATINGS, TWO-COMPONENT PACK AND COATING PROCESS BASF SE (DE) 2020-09-23 EP claimed
CN-111527155-A Quick-drying, mastic, sag resistant compositions, coatings, two-component packaging and coating processes 巴斯夫欧洲公司 2020-08-11 CN claimed
EP-0573783-B1 Multilayered polymer, process for its preparation and antistatic resin composition containing said polymer SUMITOMO CHEMICAL CO (JP) 1998-12-23 EP claimed
US-5612161-A Negatively chargable toner for electrophotography FUJIKURA KASEI CO., LTD. (JP) 1997-03-18 US claimed
US-5424370-A Graft polymerization of addition monomers and unsaturated polyalkyleneoxides SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1995-06-13 US claimed
US-5306776-A Antistatic composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-26 US claimed
EP-0573783-A1 Multilayered polymer, process for its preparation and antistatic resin composition containing said polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-12-15 EP claimed
WO-1992012213-A1 LAMINATING ADHESIVE H.B. FULLER LICENSING & FINANCING INC. (US) 1992-07-23 WO claimed
US-4990435-A Stable polymeric coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-05 US claimed
EP-0226129-B1 SILVER HALIDE PHOTOGRAPHIC ELEMENT, PHOTOGRAPHIC COATING COMPOSITION AND PROCESS TO PREPARE AN AQUEOUS DISPERSION OF A HYDROPHOBIC COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-23 EP claimed
EP-0226129-A2 Silver halide photographic element, photographic coating composition and process to prepare an aqueous dispersion of a hydrophobic compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-24 EP claimed
US-4217260-A SHELL-CORE POLYMERS WITH AMINOPHENYLTHIO-GROUPS RHONE-POULENC INDUSTRIES (FR) 1980-08-12 US claimed
EP-3838588-B2 GAS BARRIER LAMINATE AND METHOD FOR PRODUCING SAME OJI HOLDINGS CORP (JP) 2026-04-22 EP disclosed
US-4125478-A HYPOHALITE THE DOW CHEMICAL COMPANY (US) 1978-11-14 US disclosed
US-3991256-A Preparing electrostatographic printing sheet, article thereof and article coated with quaternary ammonium electroconductive resin THE DOW CHEMICAL COMPANY (US) 1976-11-09 US disclosed