Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327 | 0.92 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1302280 | 0.90 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5053935 | 0.90 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL1254117 | 0.90 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8861475 | 0.90 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8861451 | 0.90 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL165903 | 0.90 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6916022 | 0.85 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27954421 | 0.82 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11824089 | 0.81 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538078-A | USEFUL FOR HEAT EXCHANGERS; HYDROPHILIC PROPERTIES; WATER RESISTANCE; RESISTANCE TO SWELLING IN WATER; TREATMENT WITH POLYMERIC COMPOSITION THAT FORMS WATER-INSOLUBLE, THREE-DIMENSIONAL NETWORK STRUCTURE | NIPPONDENSO CO., LTD. | 1996-07-23 | — | — | US | disclosed |