SCHEMBL13023754

SCHEMBL13023754

Cc1ccc(N2c3ccccc3CCc3ccoc32)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 2/20 0.39
HTT P42858 3/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPY1R P25929 1/20 0.38
NPY2R P49146 1/20 0.38
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 6/20 0.36
ALDH1A1 P00352 3/20 0.36
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
POLB P06746 3/20 0.35
TP53 P04637 2/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023751 0.95 L3MBTL1 (0.39) GRM1HTTLMNANPC1RAB9A
SCHEMBL13023677 0.89 HTR2A (0.37) GRM1HTTLMNANPC1RAB9A
SCHEMBL13023805 0.85 MEN1 (0.40) GRM1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL13023747 0.85 MEN1 (0.39) GRM1HTTLMNAKMT2AMEN1
SCHEMBL13023773 0.85 NPC1 (0.35) GRM1HTTLMNANPC1RAB9A
SCHEMBL13023369 0.84 SMN1; SMN2 (0.45) HTTLMNANPC1RAB9ASMN1; SMN2
SCHEMBL13023744 0.82 MAPT (0.36) GRM1HTTLMNANPC1RAB9A
SCHEMBL13023782 0.80 MEN1 (0.42) HTTLMNASMN1; SMN2KMT2AMEN1
SCHEMBL13023769 0.80 HTT (0.36) GRM1HTTLMNANPC1RAB9A
SCHEMBL13023836 0.80 L3MBTL1 (0.42) GRM1HTTLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 GRM1 924/4885HTT 4114/4885LMNA 1808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.